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Artificial Intelligence in Medicine
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GKRS Stereotactic Radiosurgery System – Gamma Knife
Gamma Knife Radiosurgery (GKRS) is a non-invasive stereotactic radiation therapy technique that delivers high-dose radiation precisely to the lesion, minimizing damage to surrounding healthy tissue.
Since the establishment of the Gamma Knife Center in 2003, our hospital has accumulated experience in over 3,000 cases, serving patients with brain tumors, vascular malformations, and functional disorders. In 2024, we installed a new irradiation system and updated the radiation source. This new generation device enables more precise and intelligent calculation of safe margins and doses, shortening treatment time while maintaining accuracy.
The upgraded system integrates preoperative imaging (MRI, CT) with a new mask-based positioning technique, eliminating the need for traditional head frame fixation and the associated discomfort and wounds. Treatment can be completed on the same day, significantly reducing hospitalization time and the risk of postoperative complications. It offers patients a safer, more effective, and minimally invasive treatment option.
- Clinical Outcomes
- Case distribution: 47% benign tumors, 32% malignant tumors, 16% vascular lesions
- Patient age range: 6 to over 90 years old
- Representative outcomes
- Benign tumor control rate up to 95%, particularly in cases such as vestibular schwannomas and meningiomas
- Average cochlear dose maintained < 4 Gy, contributing to a hearing preservation rate of 89% at 1-year post-treatment
Journal Article
- Predictors of hearing outcomes following low-dose stereotactic radiosurgery in patients with vestibular schwannomas: A retrospective cohort review
https://pubmed.ncbi.nlm.nih.gov/28892717/ - Focal conformal fractionated radiotherapy vs. radiosurgery for lung cancer patients with limited brain metastases
https://pubmed.ncbi.nlm.nih.gov/33065779/ - Survival of brain metastatic patients treated with gamma knife radiosurgery alone
https://pubmed.ncbi.nlm.nih.gov/22705456/ - Outcomes and cost-effectiveness of gamma knife radiosurgery and whole brain radiotherapy for multiple metastatic brain tumors
https://pubmed.ncbi.nlm.nih.gov/19269828/ - Severe pneumocranium after gamma knife stereotactic radiosurgery for brain metastasis: A case report and literature review
https://pubmed.ncbi.nlm.nih.gov/38847695/
Monitoring mechanism
- Routine MRI follow-ups every 6 months for up to 5 years
- Outpatient follow-up to monitor for seizures, endocrine dysfunction, and psychiatric symptoms
- Utilization of the High-Definition Motion Management (HDMM) system to detect subtle patient movements with mask-based treatments
- Lightning planning system for automated dose optimization, enhancing selectivity and target coverage
- Icon Onsite Training provided to ensure optimal clinical application
Contact window
Department of Neurosurgery 018914@tool.caaumed.org.tw
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