醫師介紹
Doctor Introduction
:::
個人介紹
林彥宏 Yen-Hong Lin
助理研究員
林彥宏博士具資訊工程與生物醫學工程跨領域背景，研究聚焦於3D列印生醫材料、組織工程、再生醫學及工程化細胞外囊泡。近年致力於提升細胞外囊泡產量與生物功能，並拓展至骨再生、慢性傷口、神經修復及神經退化疾病治療
相關連結
學術論文
期刊論文
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期刊論文／Journal Paper (作者群，論文題目，期刊名稱，出版年月，卷號(期別):頁次起迄) |
日期 | |
| 1 | 郭庭佑(KUO, TING-YOU)、陳正祐(CHEN CHENG-YU)、林彥宏(Yen Hong, Lin)、周德陽(Der-Yang Cho)、林宗立(Tsung-Li Lin)*、謝明佑(Ming-You Shie)*，Lithium-doped calcium silicate scaffolds induce miR-130a-rich M2 macrophage EV-accelerating diabetic bone healing through angiogenesis–osteogenic coupling and mitochondrial repair，Chemical Engineering Journal，2026 Jul，543():178698 | 2026 . 07 |
| 2 | (Chia-Che Ho)、徐端隄(Tuan-Ti Hsu)、林彥宏、郭庭佑(KUO, TING-YOU)、陳正祐(CHEN CHENG-YU)、(Shang-Hsiu Hu)、(Jen-Ting Huang)、林宗立(Tsung-Li Lin)*、周德陽(Der-Yang Cho)*、謝明佑(Ming-You Shie)*，3D-Printed Dictamni-Calcium Silicate Scaffolds Modulate the Osteoimmune Microenvironment and Enhance Macrophage-Derived Exosomal miR-21 Signaling in Vascularized Bone Regeneration，JOURNAL OF NANOBIOTECHNOLOGY，2026 Jul，24():596 | 2026 . 07 |
| 3 | 謝明佑(Ming-You Shie)*、邱正廸(Cheng-Di Chiu)、(Yeh Chen)、林彥宏、余旻樺(YU MIN-HUA)、邱有朋(CHIU YOU-PENG)、邱伯凡(Po-Fan Chiu)、陳正祐(CHEN CHENG-YU)、陳怡文(Yi-Wen Chen)、陳美智(CHEN MEI-CHIH)、周德陽(Der-Yang Cho)*，Engineering integrin αvβ8-targeted extracellular vesicles to deliver BDNF mRNA for motor recovery in spinal cord injury，JOURNAL OF NANOBIOTECHNOLOGY，2026 Apr，24():305 | 2026 . 04 |
| 4 | 謝明佑(Ming-You Shie)*、陳美智(CHEN MEI-CHIH)、(Yeh Chen)、黃士維(Shi-Wei Huang)、林彥宏、余旻樺(YU MIN-HUA)、潘志明(Chih-Ming Pan)、陳正祐(CHEN CHENG-YU)、陳怡文(Yi-Wen Chen)、謝慶良(Ching-Liang Hsieh)、邱紹智(Shao-Chih Chiu)、高尚德(Shung-Te Kao)、林昭庚(Jaung-Geng Lin)*、周德陽(Der-Yang Cho)*，Engineered Extracellular Vesicles-Mediated Curcumin Delivery in Brain Microenvironment Modulating Lysosomes, Mitochondria, and Microglia Reprogram for Parkinson’s Disease Therapy，JOURNAL OF NANOBIOTECHNOLOGY，2026 Jan，24(): | 2026 . 01 |
| 5 | 謝明佑(Ming-You Shie)*、黃士維(Shi-Wei Huang)、(Yeh Chen)、陳美智(CHEN MEI-CHIH)、潘志明(Chih-Ming Pan)、陳正祐(CHEN CHENG-YU)、林彥宏、余旻樺(YU MIN-HUA)、甘愷雯(KAN KAI-WEN)、邱紹智(Shao-Chih Chiu)、何慧君(Hui-Chun Ho)、陳怡文(Yi-Wen Chen)*、周德陽(Der-Yang Cho)*，Engineering HLA-G-Targeted Extracellular Vesicles Nanoplatform for Enhanced Cancer Therapy through Precise Cancer Drug Delivery，Nature Communications，2025 Dec，16():11308 | 2025 . 12 |
| 6 | 余旻樺(YU MIN-HUA)、林彥宏、劉恩瑋(En-Wei Liu)、許姜太懿(Xu-Jiang,Tai-Yi)、周德陽(Der-Yang Cho)、李建智(LEE JIAN-JR)*、謝明佑(Ming-You Shie)*，Mitochondrial biogenesis modulation by silicon-stimulated mesenchymal stem cells-derived extracellular vesicles drives angio- and lymphangiogenesis in chronic wound healing，Materials Today Bio，2025 Dec，35():102629 | 2025 . 12 |
| 7 | (Po-Shun Hsu)、(Ming-Fa Hsieh)、謝明佑(Ming-You Shie)、(Wen-Ching Hsieh)、(Chun-Fan Lung)、林彥宏、(Chao-Ling Yao)、(Chien-Sung Tsai)、(Yi-Chiung Hsu)*，Decellularized porcine urinary bladder matrix as a dynamic biomaterial scaffold for myocardial cell adhesion，Journal of the Taiwan Institute of Chemical Engineers，2025 Nov，176():106325 | 2025 . 11 |
| 8 | 陳正祐(CHEN CHENG-YU)、李建智(LEE JIAN-JR)、林彥宏、郭庭佑(KUO, TING-YOU)、周德陽(Der-Yang Cho)*、謝明佑(Ming-You Shie)*，Osteoimmunomodulation of Astragalus-calcium silicate scaffolds-activated M2 macrophage-derived miR-218-rich exosome for enhanced bone regeneration，Materials Today Bio，2025 Sep，35():102286 | 2025 . 09 |
| 9 | 郭庭佑(KUO, TING-YOU)、林宗立(Tsung-Li Lin)、林彥宏、陳正祐(CHEN CHENG-YU)、周德陽(Der-Yang Cho)、陳怡文(Yi-Wen Chen)、謝明佑(Ming-You Shie)*，Lithium-Doped Calcium Silicate Scaffolds-activated M2-Polarized Macrophage-Derived miR-145-5p-Riched Extracellular Vesicles to Enhance Osteoimmunomodulation for Accelerating Bone Regeneration，JOURNAL OF NANOBIOTECHNOLOGY，2025 Aug，23():586 | 2025 . 08 |
| 10 | 陳悦生(Yueh-Sheng Chen)、李建智(LEE JIAN-JR)、林彥宏、林筠蓁(LIN YUN-JHEN)、余旻樺(YU MIN-HUA)、陳正祐(CHEN CHENG-YU)、周德陽(Der-Yang Cho)*、謝明佑(Ming-You Shie)*，Effects of magnetic fields-stimulated 3D-Schwann cell-secreted extracellular vesicles regulate differentiation of neural stem cells and nerve regeneration，MATERIALS & DESIGN，2025 Jul，255():114204 | 2025 . 07 |
| 11 | (Chia-Che Ho)、徐端隄(Tuan-Ti Hsu)、邱詠証(Chiu, Yung-Cheng)、林彥宏、謝沛橙(PEI-CHENG XIE)、(Chen-Ying Wang)*，3D-printed magnesium/strontium-co-doped calcium silicate scaffolds promote angiogenesis and bone regeneration through synergistic bioactive ion stimulation，Journal of Biological Engineering，2025 Jun，19(1):58 | 2025 . 06 |
| 12 | 林彥宏、陳正祐(CHEN CHENG-YU)、陳崑豪(CHEN KUO-HAO)、郭庭佑(KUO, TING-YOU)、林宗立(Tsung-Li Lin)*、謝明佑(Ming-You Shie)*，Lithium-doped calcium silicate cement regulates the immune microenvironment and promotes M2 macrophage polarization for enhancing bone regeneration，Journal of Biological Engineering，2025 Jan，19():3 | 2025 . 01 |
| 13 | 林彥宏、(Chen Y)、劉恩瑋(En-Wei Liu)、陳美智(CHEN MEI-CHIH)、余旻樺(YU MIN-HUA)、陳正祐(CHEN CHENG-YU)、(Ho CC)、許姜太懿(Xu-Jiang,Tai-Yi)、李建智(LEE JIAN-JR)*、周德陽(Der-Yang Cho)*、謝明佑(Ming-You Shie)*，Immunomodulation effects of collagen hydrogel encapsulating extracellular vesicles derived from calcium silicate stimulated-adipose mesenchymal stem cells for diabetic healing，JOURNAL OF NANOBIOTECHNOLOGY，2025 Jan，23():45 | 2025 . 01 |
| 14 | 李建智(LEE JIAN-JR)、林彥宏、郭庭佑(KUO, TING-YOU)、李凱星(LEE KAI XING ALVIN)、陳正祐(CHEN CHENG-YU)*、謝明佑(Ming-You Shie)*，Synergistic effects of astragalus on 3D-printed calcium silicate/poly-ε-caprolactone scaffolds to regulate inflammation/osteogenesis for bone regeneration，Materials Advances，2024 Oct，5(22):8927-8936 | 2024 . 10 |
| 15 | 陳怡文(Yi-Wen Chen)、林彥宏、(Chia-Che Ho)、陳正祐(CHEN CHENG-YU)、余旻樺(YU MIN-HUA)、李凱星(LEE KAI XING ALVIN)、邱紹智(Shao-Chih Chiu)、周德陽(Der-Yang Cho)、謝明佑(Ming-You Shie)*，High-yield extracellular vesicle production from HEK293T cells encapsulated in 3D auxetic scaffolds with cyclic mechanical stimulation for effective drug carrier systems，Biofabrication，2024 Oct，16(4):045035 | 2024 . 10 |
| 16 | (Chen-Ying Wang)、陳正祐(CHEN CHENG-YU)、陳崑豪(CHEN KUO-HAO)、林彥宏、(Tzu-Peng Yeh)、李凱星(LEE KAI XING ALVIN)、(Cheng-Chieh Huang)、謝明佑(Ming-You Shie)*，The synergistic effects of strontium/magnesium-doped calcium silicate cement accelerates early angiogenesis and bone regeneration through double bioactive ion stimulation，Ceramics International，2024 Feb，50():7121-7131 | 2024 . 02 |
| 17 | (Yi-Ling Tsai)、李建智(LEE JIAN-JR)、(Chen-Ying Wang)、林彥宏、陳正祐(CHEN CHENG-YU)、謝明佑(Ming-You Shie)*，Gallic acid–coated nanolayer on mineral trioxide aggregate for regulating the inflammatory and differentiation cellular response profile of human dental pulp stem cells，Ceramics International，2024 Jan，50():14656-14663 | 2024 . 01 |
| 18 | (Chien-Chiang Tung)、林彥宏(Lin, Yen-Hong)、陳怡文(Yi-Wen Chen)*、(Fu-Ming Wang)*，Enhancing the mechanical properties and aging resistance of 3D-printed polyurethane through polydopamine and graphene coating，Polymers，2023 Sep，15():3744 | 2023 . 09 |
| 19 | 陳怡文(Yi-Wen Chen)、林彥宏、林宗立(Tsung-Li Lin)、李凱星(LEE KAI XING ALVIN)、余旻樺(YU MIN-HUA)、謝明佑(Ming-You Shie)*，3D-biofabricated chondrocyte-laden auxetic scaffolds under cyclic tensile stimulation for cartilage regeneration，Biofabrication，2023 Aug，15():045007 | 2023 . 08 |
| 20 | 林宗立(Tsung-Li Lin)、林彥宏、李凱星(LEE KAI XING ALVIN)、郭庭佑、陳正祐(CHEN CHENG-YU)、陳崑豪(CHEN KUO-HAO)、周筠庭、陳怡文(Yi-Wen Chen)*、謝明佑(Ming-You Shie)*，The exosomal secretomes of mesenchymal stem cells extracted via 3D-printed lithium-doped calcium silicate scaffolds promote osteochondral regeneration，Materials Today Bio，2023 Aug，22():100728 | 2023 . 08 |
| 21 | 林彥宏、劉恩瑋(En-Wei Liu)、林筠蓁(LIN YUN-JHEN)、黃慧瑜(NG HOOI YEE)、李建智(LEE JIAN-JR)*、徐端隄(Tuan-Ti Hsu)*，The Synergistic Effect of Electrical Stimulation and Dermal Fibroblast Cells-Laden 3D Conductive Hydrogel for Full-Thickness Wound Healing，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2023 Jul，24():11698 | 2023 . 07 |
| 22 | 邱詠証(Chiu, Yung-Cheng)、林彥宏、陳怡文(Yi-Wen Chen)、郭庭佑、謝明佑(Ming-You Shie)*，Additive manufacturing of barium-doped calcium silicate/poly-e-caprolactone scaffolds to activate CaSR and AKT signalling and osteogenic differentiation of mesenchymal stem cells，Journal of Materials Chemistry B，2023 Apr，11():4666-4676 | 2023 . 04 |
| 23 | (Chia-Che Ho)、陳怡文(Yi-Wen Chen)、(Kan Wang)、林彥宏、(Ta-Cheng Chen)、謝明佑(Ming-You Shie)*，Effect of mussel-inspired polydopamine on the reinforced properties of 3D printed β-tricalcium phosphate/polycaprolactone scaffolds for bone regeneration，Journal of Materials Chemistry B，2023 Jan，11():72-82 | 2023 . 01 |
| 24 | (Chuan-Yi Kao)、林宗立(Tsung-Li Lin)、林彥宏、李凱星(LEE KAI XING ALVIN)、(Sing Yee Ng)、(Tsui-Hsien Huang)*、徐端隄(Tuan-Ti Hsu)*，Synergistic Effect of Static Magnetic Fields and 3D-Printed Iron-Oxide-Nanoparticle-Containing Calcium Silicate/Poly-ε-Caprolactone Scaffolds for Bone Tissue Engineering，Cells，2022 Dec，11():3967 | 2022 . 12 |
| 25 | 吳錫堯、林彥宏、李凱星(LEE KAI XING ALVIN)、郭庭佑、蔡俊灝(Chun-Hao Tsai)*、謝明佑(Ming-You Shie)*，Combined effects of polydopamine-assisted copper immobilization on 3D-printed porous Ti6Al4V scaffold for angiogenic and osteogenic bone regeneration，Cells，2022 Sep，11():2824 | 2022 . 09 |
| 26 | 李建智(LEE JIAN-JR)、黃慧瑜(NG HOOI YEE)、林彥宏、劉恩瑋(En-Wei Liu)、林亭儒(LIN, TING-JU)、邱湘庭(Chiu, Hsiang-Ting)、何欣容(Ho, Xin-Rong)、楊喜安(YANG HSI-AN)、謝明佑(Ming-You Shie)*，The 3D printed conductive grooved topography hydrogel combined with electrical stimulation for synergistically enhancing wound healing of dermal fibroblast cells，Biomaterials Advances，2022 Sep，142():213132 | 2022 . 09 |
| 27 | 李建智(LEE JIAN-JR)、黃慧瑜(NG HOOI YEE)、林彥宏、林亭儒(LIN, TING-JU)、高嘉澤*、謝明佑(Ming-You Shie)*，The synergistic effect of cyclic tensile force and periodontal ligament cell-laden calcium silicate_gelatin methacrylate auxetic hydrogel scaffolds for bone regeneration，Cells，2022 Jun，11():2069 | 2022 . 06 |
| 28 | 林彥宏、李凱星(LEE KAI XING ALVIN)、(Chia-Che Ho)、(Min-Jie Fang)、郭庭佑、謝明佑(Ming-You Shie)*，The effects of a 3D-printed magnesium-/strontium-doped calcium silicate scaffold on regulation of bone regeneration via dual-stimulation of the AKT and WNT signaling pathways，Materials Science & Engineering C-Materials for Biological Applications，2022 Jan，133():112660 | 2022 . 01 |
| 29 | 田霓(Ni Tien)、李建智(LEE JIAN-JR)、李凱星(LEE KAI XING ALVIN)、林彥宏、陳建勳(Jian-Xun Chen)、謝明佑(Ming-You Shie)*，Additive manufacturing of caffeic acid-inspired Mineral Trioxide Aggregate/poly-ε-caprolactone scaffold for regulating vascular induction and osteogenic regeneration of dental pulp stem cells，Cells，2021 Oct，10():2911 | 2021 . 10 |
| 30 | (Yi-Ting Lin)、謝明佑(Ming-You Shie)、林彥宏、(Chia-Che Ho)、(Chia-Tze Kao)、(Tsui-Hsien Huang)*，The development of light-curable calcium-silicate-containing composites used in odontogenic regeneration，Polymers，2021 Sep，13():3107 | 2021 . 09 |
| 31 | (Wei-Yun Lai)、陳衍仁(Yen-Jen Chen)、李凱星(LEE KAI-XING)、林彥宏、劉育瑋(LIU YU-WEI)、謝明佑(Ming-You Shie)*，Therapeutic effects of the addition of fibroblast growth factor-2 to biodegradable gelatin/magnesium-doped calcium silicate hybrid 3D-printed scaffold with enhanced osteogenic capabilities for critical bone defect restoration，Biomedicines，2021 Jul，9():712 | 2021 . 07 |
| 32 | 李凱星(LEE KAI-XING)、林彥宏、蔡俊灝(Chun-Hao Tsai)、(Wan-Ting Chang)、林宗立(Tsung-Li Lin)*、謝明佑(Ming-You Shie)*，Digital light processing bioprinted human chondrocyte-laden poly (γ-glutamic acid)/hyaluronic acid bio-ink towards cartilage tissue engineering，Biomedicines，2021 Jul，9():714 | 2021 . 07 |
| 33 | (Chia-Tze Kao)、邱詠証(Chiu, Yung-Cheng)、李凱星(LEE KAI-XING)、林彥宏、(Tsui-Hsien Huang)、劉彥杰(LIU, YEN-CHIEH)、謝明佑(Ming-You Shie)*，The synergistic effects of Xu Duan combined Sr-contained calcium silicate/poly-ε-caprolactone scaffolds for the promotion of osteogenesis marker expression and the induction of bone regeneration in osteoporosis，Materials Science & Engineering C-Materials for Biological Applications，2021 Jan，119():111629 | 2021 . 01 |
| 34 | (Chia-Tze Kao)、陳衍仁(Yen-Jen Chen)、(Tsui-Hsien Huang)、林彥宏、徐端隄(Tuan-Ti Hsu)*、(Chia-Che Ho)*，Assessment of the release profile of fibroblast growth factor-2-load mesoporous calcium silicate/poly-ε-caprolactone 3D scaffold for regulate bone regeneration，Processes，2020 Oct，8():1249 | 2020 . 10 |
| 35 | 涂明君(Tu, Ming-Gene)、李凱星(LEE KAI-XING)、林彥宏、(Tsui-Hsien Huang)、(Chia-Che Ho)、謝明佑(Ming-You Shie)*，Caffeic acid-coated nanolayer on Mineral Trioxide Aggregate potentiate the host immune responses, angiogenesis, and odontogenesis，JOURNAL OF ENDODONTICS，2020 Sep，46():1455-1464 | 2020 . 09 |
| 36 | 謝明佑(Ming-You Shie)、方信元(Hsin-Yuan Fang)、林彥宏、李凱星(LEE KAI XING ALVIN)、(Joyce Yu)、陳怡文(Yi-Wen Chen)*，Application of piezoelectric cells printing on three-dimensional porous bioceramic scaffold for bone regeneration，International Journal of Bioprinting，2019 Dec，5():210 | 2019 . 12 |
| 37 | 林彥宏、(Tsan-Yu Chuang)、(Wei-Hung Chiang)、(I-Wen Peter Chen)、(Kan Wang)、謝明佑(Ming-You Shie)、陳怡文(Yi-Wen Chen)*，The synergistic effects of graphene-contained 3D-printed calcium silicate/poly-ε-caprolactone scaffolds promote FGFR-induced osteogenic/angiogenic differentiation of mesenchymal stem cells，Materials Science & Engineering C-Materials for Biological Applications，2019 Oct，104():109887 | 2019 . 10 |
| 38 | 邱詠証(Chiu, Yung-Cheng)、謝明佑(Ming-You Shie)*、林彥宏、李凱星(lee kai xing alvin)、陳怡文(Yi-Wen Chen)*，Effect of strontium substitution on the physicochemical properties and bone regeneration potential of 3D printed calcium silicate scaffolds，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2019 Jun，20(): | 2019 . 06 |
| 39 | 吳源晧(Yuan Haw (Andrew)Wu)、邱詠証(Chiu, Yung-Cheng)、林彥宏、何佳哲(Chia-Che Ho)、謝明佑(Ming-You Shie)、陳怡文(Yi-Wen Chen)*，3D-printed bioactive calcium silicate/poly-ε-caprolactone bioscaffolds modified with biomimetic extracellular matrices for bone regeneration，INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES，2019 Jan，20():942 | 2019 . 01 |
| 40 | (Kuo-Hao Huang)、陳怡文(Yi-Wen Chen)、(Chen-Ying Wang)、林彥宏、吳源晧(Yuan Haw (Andrew)Wu)、謝明佑(Ming-You Shie)*、(Chun-Pin Lin)*，Enhanced Capability of Bone Morphogenetic Protein 2–loaded Mesoporous Calcium Silicate Scaffolds to Induce Odontogenic Differentiation of Human Dental Pulp Cells，JOURNAL OF ENDODONTICS，2018 Nov，44():1677-1685 | 2018 . 11 |
| 41 | (Kuo-Hao Huang)、林彥宏、謝明佑(Ming-You Shie)*、(Chun-Pin Lin)*，Effects of bone morphogenic protein-2 loaded on the 3D-printed MesoCS scaffolds，JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION，2018 Sep，117():879-887 | 2018 . 09 |
| 42 | 林彥宏、邱詠証(Chiu Yung-Cheng)、(Shen Yu-Fang)、吳源晧(Yuan Haw (Andrew)Wu)、謝明佑(Shie, Ming-You)*，Bioactive calcium silicate/poly-epsilon-caprolactone composite scaffolds 3D printed under mild conditions for bone tissue engineering，JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE，2018 Jan，29():11 | 2018 . 01 |
研討會論文
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研討會論文／Conference Papers (發表主題或論文名稱，研討會名稱，演講地點，研討會期間，受邀演講題目) |
日期 | |
| 1 | A Novel Approach to Large-Scale Extracellular Vesicle Production by Biofabrication Auxetic Hydrogel，TSBME 2023 Annual Symposium of Taiwanese Society of Biomedical Engineering Project Report of National Science and Technology Council，中原大學，2023.11.11~2023.11.12， | 2023 . 11 |
| 2 | Mechanotransductive Enhancement of Extracellular Vesicle Production using Auxetic FGelMA Hydrogel for Cancer Therapeutics，2023 Materials Research Society-Taiwan International Conference，清華大學，2023.11.17~2023.11.20， | 2023 . 11 |
| 3 | Cyclic Tensile Mechanical Stimulation Enhances Cartilage- related Matrix Formation of Bioprinted Chondrocyte-laden Auxetic scaffold，再生醫學治療之最新發展:從基礎研究到國家法規制定暨2023年台灣再生醫學學會學術研討會，台大醫院國際會議中心，2023.03.25~2023.03.25， | 2023 . 03 |
| 4 | Enhancement of Biofunctionality to Bone Tissue Regeneration by 3D Printing Multi-Calcium Silicate Scaffolding Architecture，2020 International Symposium of Materials on Regenerative Medicine，國立成功大學，2020.12.12~2020.12.13， | 2020 . 12 |
| 5 | The physicochemical properties and cell behavior of biodegradable 3D-printed calcium silicate scaffolds，5th TERMIS World Congress，Kyoto, Japan，2018.09.04~2018.09.07， | 2018 . 09 |
專書
暫無資料研究計畫
暫無資料專利技術
暫無資料獲獎事蹟
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獲獎／Award (獲獎名稱，給獎單位，獲獎日期) |
日期 | |
| 1 | 2021生物醫學工程科技研討會-最佳口頭報告獎，中華民國生物醫學工程學會，2021.11.20 | 2021 . 11 |
| 2 | 2020 ISOMRM Poster Award-Outstanding，International Symposium of Materials on Regenerative Medicine，2020.12.13 | 2020 . 12 |
| 3 | 中華牙醫學會牙醫科學期刊傑出論文獎，中華牙醫學會，2018.10.20 | 2018 . 10 |
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